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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418108dddbeca5e97b350e33c1df436480c55142b0ba15062ba9bc8006c731ff' 
  AND token = 'kdqhmG5KToZ6+31UnqhfZWxA9aMlV7NLLQZSWgsLD5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}