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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ba650a0dd956888ff5fce2b7acb1a982651163fd5049f75e312c5a50eb3ca65' 
  AND token = 'VsCqc/zErQCYcYEoxujUU6qDE8n000pFzz5dAB35Kks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}