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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c1b0d3fd041ecb5d8d941f6bf9b4a3294a9ffa7af69664aa85a66720c5482c' 
  AND token = 'sC1eDyUbjL34uRq40nINLtg1Sku2x2UN3dHK/4Z+KN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}