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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0fd2603d2de869133750267d0642766f4b1704728ae0bf724ecda9a8b8bef8d' 
  AND token = 'MQh8uQszxyupIPdwDFzS0kYWjN7SqcWBOs9YjQMB8Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}