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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbcb6e8d08233a4186912ce08eb8c2d4050fa0e37e132fa811d785f27dc1020c' 
  AND token = 'tixayxdBJzLMAWMT6Xx5nqVUozqSHQXHYjLso8qjcRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}