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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a890307953ddd7e6337904b7f43e611be64a3e861ff4c641f84a2e2542e4226' 
  AND token = 'SW1o7eMi+TAtILC+5io24JB9EH3NPOnmTTyLRqZOrzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}