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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d07dbf908abbe6d621b0be88a711eb51b476312f3b9621758decbfb40116dad' 
  AND token = 'QAF/FQOBtq4zDJvfnr6MKkzNxbdz2u5erEH9YPsbEcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}