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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca249ef982f7ba4bbe01ba15185cde3fe80b90ce14a842b5ff1c4a8177b8d26' 
  AND token = 'fZBzGHm4cJl/9krgBRSHtw8pHECUWc6D9VIaB2H/oB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}