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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd9b2ae56a396c9b8e7c4c8ce7c5dc6bd5769822f941416545ba237bb010726' 
  AND token = 'TNg+7C2+f18Ly/UxFXGPVdWcyY+4v1SKPfSy2/9dauk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}