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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3a887390324c8d44b6540d178177125a053a92610c4c1d22255ee2f62ff4a1' 
  AND token = 'GxCxPCc9xNe5bSrDzWnClkPgXczIEdnqn10p2M8QHMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}