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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a5e6ab9836b3a3b873787d47c9b764e4a7d4ef12e9f6b5caede36dff375bd9' 
  AND token = 'WpFH7pKGgIEhLA35uK7B97oYBEHqyZgVWLV5XsWRbcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}