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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40144a60091bf61adce17cff5f38a2e35dca616dd30829e499412d5325c6e29d' 
  AND token = 'MATpbPXsKlL6pTiiLkH1Zbs8cnsr+De6HyAHB2lzfBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}