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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac28632802e5a1b3e20dff5668ade2856c452455a7a6e7b837b0142addff0a3' 
  AND token = 'eiL+2w7tL5eHobMj7BG2gm1OHBZX8gDyoLoFMPPQZao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}