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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99daa4c1b9a40a7f1490f302708bc005e2fad4ef545eb07b59b54a7d776008e1' 
  AND token = 'ap3p1Az8JGqTIKsMi6FJ8ieMZ4YyikJcFPpjxiWbqRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}