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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11a1354ed4b9d3ad0c6fc760139a126aba78db5e0356eb7946d22a69ede51dec' 
  AND token = '5NmdiYoME7yp0EOzdShsXofB5tgQ6Wl3NyZNvbIDQvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}