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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d25b2eb3e224f81a040ed5b7a51019ed3475fa81fa9b4ae7ac729b910af497' 
  AND token = '7J8MgoispGje34BT++evAd43tx3iivj7KOfRpiBkjpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}