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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47d4f0891be5648ec70816b35edc1580d9a7fef680cbed83a20a25580b4e7041' 
  AND token = 'XoPi0Lgccw1TSgQ5smA8tUmto82AkSG0P8qOYO4/+8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}