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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fd13baffbd86782836c2985052ca4860b654b62ce99129befe2dbcb4dc35e2' 
  AND token = 'Fd3S7I4NnmhhnV/3rzux3pPZtt1wI/A9201PffCVXw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}