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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d5be9aabfc13f1afd2ebd0c663476d12bd7fa519945581cff44b23a218f3b6' 
  AND token = 'Nu01WeMSztXaNDWx+Z4wh5l0e0SNq7Kbq07ss5M6Ne4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}