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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4534a5e3be01a5359bdbf532f5b959235693dd77931b7e31d35ab03f28e636fc' 
  AND token = '1kz3xB5n3qv5fLd8MsnYfI3BgAHiMHVMk5YVCN1dm/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}