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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7afeeb5cf0c00369e6407ab983b79c146d497458f2350a9d261aae6a2d135491' 
  AND token = 'nA1EUmwfx8Dguc1ZbA3Oyd8gJM3FC/QV0aqVovLMh7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}