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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd735d1cdb6a5c9c16f73581921b34d10fe431ce66551b6965ff402f4d4a5a016' 
  AND token = '+J0Nz2nqWrrUXXuw9MZmQjabO/m6Hj6tMbnzOr7Gg6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}