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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e609b9fc230ab76f61365f64742505410c8666f0f4c70c4f654da1b564b072f' 
  AND token = 'Pqv0hmDzl8ek26JXqEyJxr+olmpqJydc0laJn624NNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}