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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e541f799e4551bc1fc66f5a1a17b9c2951149db9deea6948fb3deafb6edb78b' 
  AND token = 'qF6/CHHa94U9n1+ixP+xKuYenWmxXvx3C4tOWjwf72k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}