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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59142221e765d17ece7719ea5cbec4edd10f56d9e484ad70415e1db18a60b47a' 
  AND token = 'FBKAVLB7om6IsYxrj0wHM8a+ATv57jjY3Xq1bd+RkzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}