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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1eaf50e9a45e9e81263a9f1c4b56ba671136198466a1410d814e15c28414bb' 
  AND token = 'JYKcMC7LjI6xnpKu3C454lAq/adjGxunIqt4fnF3Af8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}