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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6dac6fb84fd7a0ed66946358904373aae8a0457ad8e0d27dde60e387f94f5d' 
  AND token = 'NWoPRzN5IHMAQ5BbPx7Rs6XmIQJzwOacGAnq0XDrINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}