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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0cc1f8fb6c82c51ef8dd24f477db7028554579c52012907cab9b89af8d80ba' 
  AND token = 'GsdD507YJ2UaQUNlSbxYZu0enlrSEznVM91MEyDTnA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}