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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200e60fb23cbd0f7d2b0aa9b9b200ea5cc784fa2353e76ce9ea01f7774f34628' 
  AND token = 'cwQXg0xIk0CUTJ1kLTjGfhygTW4qtwN86tzvRfDFPCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}