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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161526e633bd77dd5875066b71d05cf200677317912b90b179d20e9e0bbd3461' 
  AND token = '7IbzKmq6X4bpjm2F5sHNfqZ7Jouvlb2ydCKj8h6XBUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}