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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e35f16e3d8514c95a90ff7bfdf2be4928a7b44657b7ed65de23e1dcdd925bd' 
  AND token = 'FXRDAX3XZ6a0oHKPbmDX/EZF00sD/qG5teIjPEj+o8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}