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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c42f9b7df433d5e1a9a3d90628c67535913ebd28da4ac07a3a5ab3d6c35680b' 
  AND token = 'UiLS4yFMbiS89Pn1xmylm6rx+PkSf4v8dtNSwnVTRDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}