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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c94dd5ca65a496a06845e49b6437115b5f3abb0e38530ec5f28d22930d3c3ff' 
  AND token = 'RuHWi9hyy6t6iOjATnYI3n2/uVMYQKePZlbrkvmWdG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}