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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c174b70c1dba92380d9ffad01d77c184c3721ee57fa44c106c08c1c1c424ed' 
  AND token = '5y1Lbmqkv9Q53BRptN5y8ShK/HUppnfaV0s6Yn1K8Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}