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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae75bdcb519ddbdc9c2ae1d74c4ee23967b9ce70cf210e0c6ba5312122169800' 
  AND token = 'VCBZ77tQH5602uxGFNHGVUQx7fZQgzz6ingS+yx4xEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}