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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b06845aa313dabd832b88ad1d117d56f31662e9b934823d2177c289cdb12e668' 
  AND token = 'OM/2YpGUHmrwmd2eHKD88d3ad/UEExAdRFJDhTIoLs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}