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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4976469e800098d39b56691007d7f0255fb1f766f76f63f5b6fdf5acecd4340f' 
  AND token = 'Gww1h8cAuRb3gn7RD+V5Wp01hUBvsO/RI5Ll3//1Muo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}