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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453c3c79c0fe4373c5419477ac73a8ead8579164d656a5e0a7554a8021d579aa' 
  AND token = '9IkRWpbASFMh7i2J6aU6OLUtOnYknQUjer6cv5ebOa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}