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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97c387ac15d758447b4648345e3e4003d11ea5f5b714195e4b728868bde3784b' 
  AND token = 'tAMvBPX9MfUyqtp4PeEZ3I5WYKwSE8Fipwodmj/OMiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}