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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5798ad74dd73070a9a6a884f93f13f7b9c3d1b73c45d92394e10066aa51e2d1' 
  AND token = 'pLqJh1h4o+Dp1L/nKPdGhCjQJ9TQijkhuaEKXY5jNi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}