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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d4d47dfa00e25bd4d5bdb4befadeb4e1a428257d4854cb28783fa727f3b0e7' 
  AND token = 'fw1Q/C1A1rfMzfiQ/YTEHyk+vpIr7i215eD3n7laefo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}