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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fec7a0c6311be5c7348317b0cf02e3ed1ff9a1b656201f12abcff914627d416' 
  AND token = 'X+1auz4kOcJExY3KTqyCmTIMub5OYj58QQnuK5i92Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}