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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88bf0d119c8a96b7e1a0500b898e3f042b05b734b970628868f3b9002164c217' 
  AND token = 'F4pOyfyXRdGDZKZEgEvjLnjPr59mdjudkvE9Zo2Z3W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}