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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1675610c822a9af641605a6b38f7e57f429f8ce47066255f2937c7de635f9b97' 
  AND token = '6JQHLm7wMyIthf+bgZWoJuP/klRe0zEb6ubc3sahZMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}