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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ddad55b4a86dbb95b0202fcf586906a58b8fe99ddf3066c70da8afcfee980a' 
  AND token = 'scKdjzSwLYYGhChQ/f4qV/VZh+C60UuNvtTW8U0NYaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}