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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d502686d1f3d4d76482f1e8b15379efbc7a75291d11f7efe220c82e1889de0c' 
  AND token = 'Ki62s11IOlq/Na2ajzfLWxQ2bHM6grwgJGs8fxlfZWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}