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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad783c86b6a0dd2191fac069c7719642d639026f5cc4f395339dd05ada9aea2d' 
  AND token = 'am9gfTcVazVEw0x+Cx84uXYgYXYp2nLlyl/L84wlVX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}