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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f1f171147c90415945bb9de0b7c5cca9e97866a5caf79982cc5c2fc872b0d1' 
  AND token = 'nntjl5r3XWKpT7c4SuGsveAXGSJai/XlgkfsoGX12wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}