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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '398ef659bdc4232cdc5afe853245ecc9ec161b7ab478de41d19f6ba185ae001d' 
  AND token = 'HW9O5yk8T3Hc1BFJ9JTDT218jE0o17qBRx1DIAS1Xwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}