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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80e7b109959df966220160f0a1b86e09cde901f4499364563e73720db26b109' 
  AND token = 'vPZV2ntGTh9Aq2Y5elaVAZ2sa0eSPfB/1WJIQJW8/Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}